Here is a list of the Top Oxidative Stress Tests available for evaluating your lifestyle choices. These tests measure the level of different biomolecules that provide evidence of Oxidative Stress. Oxidative Stress is thought to the the primary cause of multiple health problems. Blood Oxidative Stress or BLOS is thought to be the main source of Oxidative Stress in humans. If we have any hope in managing BLOS, then we need a way to measure its level.
What is Oxidative Stress? Let’s review the two sources of Oxidative Stress and determine which source is more important. General Oxidative Stress is thought to be the only source of Oxidative Stress. However, Blood can also generate Oxidative Stress, which is also known as BLOS. This post provides information about why BLOS is more important compared to General Oxidative Stress. EBooks (and Books) and BLOS Health Hack Kits may help you fight BLOS for better health.
General Oxidative Stress
The mechanistic model of General Oxidative Stress starts with an elevated rate of metabolism that results in mitochondrial dysfunction. In turn, this leads to an increased production of reactive oxygen species (ROS). Medical researchers observe General Oxidative Stress in tissue cultures, but it is difficult to observe in the human body. How many biopsies are needed to identify the tissues sources of General Oxidative Stress? Instead, medical researchers rely on diagnostic methods that evaluate ROS or oxidation end products in blood, urine, or breath.
General Oxidative Stress and ROS
ROS includes O2− (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Most folks are familiar with the many uses of hydrogen peroxide for cleaning, disinfecting, and more. For your health, excessive production of ROS including hydrogen peroxide can be dangerous. The ROS molecules diffuse into the bloodstream and react with biomolecules throughout the body. The end products of these ROS reactions can be measured in blood, urine, and breath. The general consensus on the primary cause of General Oxidative Stress is the high caloric content of the Western Diet.
Excessive alcohol consumption is a special case of General Oxidative Stress. It causes short periods of ROS generation in the liver and other organs. Short periods of ROS generation is a primary characteristic of General Oxidative Stress. It is due to the reliance on excessive substrate availability necessary for the elevated rate of metabolism. A second source of Oxidative Stress is from blood cells, which received little attention from medical researchers or the general public.
Blood Oxidative Stress
White blood cells and platelets can generate high rates of ROS, which is alarming when the patient does not have an infection. In 2008, Walter Paulus’ research group reported on ROS+ blood cells in both healthy (non-hospitalized) and congestive heart failure (CHF) patients. Here is the link for the Abstract of the research article describing Blood Oxidative Stress or BLOS: https://www.ncbi.nlm.nih.gov/pubmed/18957960 This article provides interesting BLOS data and I will focus on the most important findings, which escaped the attention of the researchers. The research community missed it, but this is understandable when you consider that there are over 200,000 research articles about Oxidative Stress. The Paulus’ paper is the proverbial “needle in the haystack” for Oxidative Stress.
Hypertension is one of many health problems associated with Oxidative Stress. In the fight against Oxidative Stress, improved fitness often takes the backseat to dietary changes. Some folks think that a regimen of low-dose aspirin will reduce their risk of heart attack or stroke. Recent research suggests that this idea is wrong. The idea of exercise is dreadful for most people, especially as they get older and life gets more complicated. This post provides information on a simple fitness tip that reduces Hypertension. Always consult with your physician before making any changes in your exercise routine and diet (read our Disclaimer below).
A review of the current medical research suggests that three Antioxidant Supplements may reduce Oxidative Stress for improved health.
The two reported sources of Oxidative Stress are General and Blood Oxidative Stress or BLOS. General Oxidative Stress is the more familiar due to its earlier discovery. However, BLOS is probably the primary cause of Oxidative Stress. General Oxidative Stress results from short periods of elevated metabolism rates within cells that generates reactive oxygen species (ROS). In contrast, BLOS is a large fraction of your blood cells induced to generate high levels of ROS. Long term, elevated BLOS is the probable cause of multiple health problems. More than 2/3 of adult Americans suffer from BLOS. Both sources of Oxidative Stress result in high levels of ROS that diffuse throughout the body causing damage and health problems. Although your body does produce low levels of antioxidant, excessive ROS may require an antioxidant supplement to manage Oxidative Stress.
Here is a list of the Top 5 Foods to avoid, if you want to reduce Oxidative Stress and improve your health. Avoiding ultra-processed foods may reduce your risk of cancer, but are they all bad for you? Many ultra-processed foods have one thing in common: high levels of inorganic sulfur. This type of sulfur leads to the growth of sulfate reducing bacteria (SRB) in your gut, which may cause your blood cells to generate high levels of reactive oxygen species (ROS), the primary source of Oxidative Stress. In the long term, high levels of ROS can damage DNA, which can cause cancer.
BLOS World provides a review of the best information and products to reduce Oxidative Stress. Why should you worry about Oxidative Stress? Start with learning more about Oxidative Stress generated by your blood.
What is Blood Oxidative Stress?
Blood Oxidative Stress (BLOS) is probably the primary cause of Oxidative Stress. In BLOS, activated blood cells generate high levels of reactive oxygen species (ROS). However, reducing the amount of inorganic sulfur in the diet and adding effective antioxidant supplements may manage BLOS. About 2/3 adult Americans are thought to suffer from elevated BLOS. BLOS extends beyond the USA with Europe and countries that adopted the Western Diet. The effective management of BLOS may be the key to treating several health problems including Obesity, Type 2 Diabetes, Hypertension, and the risk of Cancer. In the USA, BLOS is thought to be responsible for annual healthcare costs of more than $800B.